- 產品說明
- 產品細節
◆ Cryopreserved ready-to-use
冷凍保存細胞與 vesicles，解凍後即可使用，無需自行建立 stable cell lines
◆ ２天內完成 assay
SLC transporter cells 解凍貼壁後約 48 小時即可進行 uptake assay
◆ 高表現單一人類 transporter
HEK-293 transient overexpression 系統，每個 cell line 僅表現單一 human transporter
Uptake ratio ≥10，post-thaw viability >80%
◆ 符合法規導向
設計用於 transporter DDI 評估，支援 ICH M12 drug interaction recommendations
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SLC Uptake Transporter Cells（進細胞） |
ABC Efflux Vesicles（出細胞） |
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Cryopreserved HEK-293 cells，單一 human SLC transporter 表現：
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Inside-out membrane vesicles，用於 ATP-dependent efflux assays：
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用途：
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用途：
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Gentest TransportoCells™ are high-performance mammalian cells in a convenient, cryopreserved format that transiently overexpress a single human SLC transporter protein.
TransportoCells™ (SLC uptake transporters) are cryopreserved, and they are thawed, plated, and cultured for 24 hours prior to use.
|
Catalog Number |
Transporter(s) |
Description |
Gene Accession Number |
Cell Count |
|
354851 |
OATP1B3/SLC01B3 |
Organic anion-transporting polypeptide 1B3 |
NM_019844 |
>10 Million |
|
354852 |
OCT1/SLC22A1 |
Organic cation transporter 1 |
NM_003057 |
>10 Million |
|
354853 |
OCT2/SLC22A2 |
Organic cation transporter 2 |
NM_003058 |
>10 Million |
|
354854 |
Vector Control |
Vector control cells |
N/A |
>10 Million |
|
354855 |
MATE1/SLC47A1 |
Multidrug and Toxin Extrusion transporter 1 |
NM_018242 |
>10 Million |
|
354856 |
MATE2-K/SLC47A2 |
Multidrug and Toxin Extrusion transporter 2-K |
NM_001099646 |
>10 Million |
|
354857 |
OAT1/SLC22.A6 |
Organic anion transporter 1 |
NM_004790 |
>10 Million |
|
354858 |
OAT3/SLC22.A8 |
Organic anion transporter 3 |
NM_004254 |
>10 Million |
|
354859 |
OATP1B1*1a/SLC01B1*1a |
Organic anion-transporting polypeptide 1B1, Wild Type (388A) |
NM_006446.4 |
>10 Million |
|
354860 |
PEPT1/SLC15A1 |
Peptide transporter 1 |
NM 005073 |
>10 Million |
|
354861 |
PEPT2/SLC15A2 |
Peptide transporter 2 |
NM_021082 |
>10 Million |
|
354862 |
OATP2B1/SLC02B1 |
Organic anion-transporting polypeptide 2B1 |
NM_007256 |
>10 Million |
|
354864 |
NTCP/SLC10A1 |
Nao-taurocholate cotransporting polypeptide |
NM_003049 |
>10 Million |
|
354866 |
OCTN2 |
Organic cation/carnitine transporter 2 |
NM_003060 |
>10 Million |
|
354867 |
OAT2 |
Organic anion transporter 2 |
NM_006672 |
>10 Million |
|
354868 |
OAT4 |
Organic anion transporter 4 |
NM-018484 |
>10 Million |
TransportoCells™ Vesicles (ABC efflux transporters) are stored at -80ºC, and they are thawed and used like a Supersome®.
|
Catalog Number |
Full Name |
Gene Accession Number |
Size |
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453800 |
TransportoCells™ HEK Control Vesicle |
N/A |
0.5 mL |
|
453801 |
TransportoCells™ HEK Human MDR1/P-gp Vesicles |
NM_000927 |
0.5 mL |
|
453802 |
TransportoCells™ HEK Human BSEP Vesicles |
NM_003742 |
0.5 mL |
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453803 |
TransportoCells™ HEK Human MRP2 Vesicles |
NM_000392 |
0.5 mL |
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453804 |
TransportoCells™ HEK Human BCRP Vesicles |
NM_004827 |
0.5 mL |
|
453805 |
TransportoCells™ HEK Human MRP3 Vesicles |
NM_003786 |
0.5 mL |
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453806 |
TransportoCells™ HEK Human MRP4 Vesicles |
NM_005845 |
0.5 mL |
|
459010 |
MRP/BCRP vesicle assay kit |
N/A |
Up to 200 assays |
|
459011 |
BSEP vesicle assay kit |
N/A |
Up to 200 assays |